Morpholino PMO / Activated Subunits
O6-(p-tolyl pivalate)-N2-PhAc protected G PMO Monomer
Quick view. An Activated DPG guanine PMO monomer bearing N2-phenylacetyl, O6-(p-tolyl pivalate), morpholine N-trityl, and dimethylphosphoramidochloridate groups. CAS 1155309-89-9. Catalog target purity: Specification by inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Catalog status
Scope. "Available for inquiry" is not a stock claim. Operating tier is a catalog-merchandising priority. Development phase and program context are shown only where the reviewed catalog source provides a mapping; they describe the chemistry platform and do not claim that OROGO supplies the named program. Annual demand is a planning-model estimate from the reviewed demand dataset, not OROGO sales, inventory, a guaranteed market size or a supply commitment.
| Supply status | Available for inquiry |
|---|---|
| Operating tier | Core |
| Reviewed supporting program count | 4 |
| Representative chemistry-platform program | casimersen |
| Planning-model annual demand | 262.6 kg/year |
| Demand estimate basis | Planning model: current marketed plus clinical-stage programs |
| Highest development phase | Marketed |
| CAS status | Published registry number |
Product profile
O6-(p-tolyl pivalate)-N2-PhAc protected G PMO Monomer is classified as protected guanine morpholino phosphoramidochloridate (Formula C51H53ClN7O7P; molecular weight 942.20).
O6-(p-tolyl pivalate)-N2-PhAc protected G PMO Monomer — Protected guanine morpholino building block for research-use PMO synthesis.
For O6-(p-tolyl pivalate)-N2-PhAc protected G PMO Monomer, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- Activated DPG Subunit
Useful catalog search terms
- 1155309-89-9
Physicochemical data
| N2 protection | Phenylacetyl |
|---|---|
| O6 protection | p-Tolyl pivalate |
| Morpholine nitrogen protection | Trityl |
| Phosphorus group | Dimethylphosphoramidochloridate |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
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