# OROGO

Content last reviewed: 2026-10-13.

OROGO is the nucleoside-compound team of Chongqing Botao Biotechnology Co., Ltd. Founded in 2013, OROGO develops and supplies nucleosides, nucleotides, oligonucleotide building blocks and specialty research materials, with process development and gram-to-kilogram scale-up support.

OROGO serves qualified research institutions and pharmaceutical or biotechnology companies. Website products and services are research-use and non-GMP.

## Catalog scope
- 243 public catalog records across 47 populated platform-and-product-form directory pages.
- 243 products have indexable, self-canonical English routes; 19 canonical English technical articles are eligible for indexing. Current indexable URLs are listed in https://orogo.com/sitemap.xml.
- Product and taxonomy-directory locale routes reuse one reviewed English technical record and render that managed body with lang="en". Until a reviewed technical translation exists, each prefixed locale route is noindex, follows links, canonicalizes to the unprefixed English route and stays out of the sitemap and hreflang cluster. Article fallbacks use the same English-canonical noindex boundary.

## Machine-readable product data
- Every product page exposes a schema.org Product record with its public OR catalog number and current reviewed catalog fields.
- Bioschemas MolecularEntity markup is emitted only when the exact catalog-product form and its structure identifiers have passed publication review. Missing MolecularEntity fields are intentionally omitted and must not be inferred.
- MolecularEntity records may include CAS, molecular formula, molecular weight, InChI, InChIKey, SMILES, PubChem CID and ChEBI identifiers. A sameAs URL is present only when the external record has been reviewed as the same exact published identity.
- Product structured data does not claim a public price or in-stock status. Availability, pack size, current specification and lot documentation are confirmed by inquiry.
- Canonical product URLs use /products/<slug>; public catalog numbers use the OR- prefix and should be used when requesting or citing a catalog record.

## Main product families
- https://orogo.com/products/2-fluoro/phosphoramidites — 2′-F / Phosphoramidites (16 products)
- https://orogo.com/products/2-o-moe/phosphoramidites — 2′-MOE / Phosphoramidites (6 products)
- https://orogo.com/products/2-o-methyl/phosphoramidites — 2′-OMe / Phosphoramidites (19 products)
- https://orogo.com/products/dna/phosphoramidites — DNA / Phosphoramidites (9 products)
- https://orogo.com/products/rna-tbdms/phosphoramidites — Natural RNA / Phosphoramidites (4 products)
- https://orogo.com/products/mrna-delivery/caps — mRNA and Delivery / mRNA Cap Analogs (1 products)
- https://orogo.com/products/galnac-ligand/phosphoramidites — GalNAc Ligands / Phosphoramidites (3 products)
- https://orogo.com/products/cycle-reagents/reagents — Synthesis-Cycle Reagents / Coupling Activators (3 products)
- https://orogo.com/products/stereopure-ps/phosphoramidites — Stereodefined PS / Phosphoramidites (30 products)

## Key pages
- https://orogo.com/catalog — complete product catalog
- https://orogo.com/technology-platforms — stereocontrolled phosphorothioate chemistry, nucleoside and oligonucleotide building blocks, GalNAc conjugation, cyclic dinucleotides, glycochemistry, sulfurization and activation reagents, analytical standards and custom synthesis
- https://orogo.com/services — custom chemistry services, process development, scale-up, non-GMP tox material and reference standards
- https://orogo.com/company — company profile: founded in 2013, nucleoside-focused R&D, two R&D bases, 50+ R&D staff and gram-to-kilogram scale-up support
- https://orogo.com/quality — enterprise quality policy, ISO 9001, ISO 14001 and ISO 45001 certificates, downloadable supplier-qualification documents, EHS approach and project-specific quality documentation
- https://orogo.com/resources — product selection guides, quality documentation notes, application notes and custom request checklists
- https://orogo.com/news — technical articles and industry analysis on nucleoside chemistry, oligonucleotide raw materials and scale-up
- https://orogo.com/support — quote support, technical support, custom chemistry intake and documentation request guidance
- https://orogo.com/privacy — privacy notice for contact and project information
- https://orogo.com/terms — website and research-use terms

## Current technical articles
- https://orogo.com/news/apoc3-oligonucleotides-two-regulatory-tracks — APOC3 Oligonucleotides Advance on Two Regulatory Tracks
- https://orogo.com/news/how-to-choose-nucleoside-intermediates-for-scale-up — How to Choose Nucleoside Intermediates for Scale-Up
- https://orogo.com/news/key-quality-attributes-for-modified-nucleotides — Key Quality Attributes for Modified Nucleotides
- https://orogo.com/news/sulfurizing-reagents-for-oligonucleotide-synthesis — Sulfurizing Reagents for Oligonucleotide Synthesis
- https://orogo.com/news/process-development-challenges-in-nucleoside-manufacturing — Process Development Challenges in Nucleoside Manufacturing
- https://orogo.com/news/what-to-consider-when-sourcing-cap-analogs — What to Consider When Sourcing Cap Analogs
- https://orogo.com/news/novartis-paid-12-billion-for-avidity-the-structure-is-the-interesting-part — Novartis Paid $12 Billion for Avidity. The Structure Is the Interesting Part.
- https://orogo.com/news/enzymatic-dna-synthesis-what-it-threatens-and-what-it-does-not — Enzymatic DNA Synthesis: What It Threatens, and What It Does Not
- https://orogo.com/news/established-chemistry-buys-you-a-smaller-regulatory-package — Established Chemistry Buys You a Smaller Regulatory Package
- https://orogo.com/news/oligonucleotide-capacity-is-measured-in-moles-and-the-numbers-are-small — Oligonucleotide Capacity Is Measured in Moles, and the Numbers Are Small
- https://orogo.com/news/what-the-data-says-about-stereodefined-phosphorothioate — What the Data Says About Stereodefined Phosphorothioate
- https://orogo.com/news/cyclic-dinucleotides-why-the-backbone-is-sulfurized — Cyclic Dinucleotides: Why the Backbone Is Sulfurized
- https://orogo.com/news/galnac-linker-chemistry-for-oligonucleotide-research — GalNAc Linker Chemistry for Oligonucleotide Research
- https://orogo.com/news/arrowheads-p-s-detour-to-a-5-prime-cyclopropyl-phosphonate — Arrowhead's P=S Detour to a 5′-Cyclopropyl Phosphonate
- https://orogo.com/news/antibody-oligonucleotide-conjugates-three-coupled-development-problems — Antibody-Oligonucleotide Conjugates: Three Coupled Development Problems
- https://orogo.com/news/rna-based-skincare-materials-question — RNA-Based Skincare Is Becoming a Materials Question
- https://orogo.com/news/interpath-001-positive-phase3-result — INTerpath-001 Is Positive, but the Phase 3 Effect Size Is Still Missing
- https://orogo.com/news/coupling-activators-in-oligonucleotide-synthesis — Coupling Activators in Oligonucleotide Synthesis: Reading the DCI Evidence Carefully
- https://orogo.com/news/2-fluoro-phosphoramidites-and-duplex-behavior — 2′-Fluoro Phosphoramidites: From Solid-Phase Synthesis to Duplex Behavior

## Additional product families
- https://orogo.com/products/s-cet/nucleosides — (S)-cEt / Nucleoside Intermediates (5 products)
- https://orogo.com/products/s-cet/phosphoramidites — (S)-cEt / Phosphoramidites (4 products)
- https://orogo.com/products/2-fluoro/nucleosides — 2′-F / Nucleoside Intermediates (11 products)
- https://orogo.com/products/2-o-moe/nucleosides — 2′-MOE / Nucleoside Intermediates (11 products)
- https://orogo.com/products/2-o-moe/succinates — 2′-MOE / Succinates (5 products)
- https://orogo.com/products/2-o-methyl/nucleosides — 2′-OMe / Nucleoside Intermediates (11 products)
- https://orogo.com/products/2-o-methyl/succinates — 2′-OMe / Succinates (4 products)
- https://orogo.com/products/dna/nucleosides — DNA / Nucleoside Intermediates (2 products)
- https://orogo.com/products/dna/succinates — DNA / Succinates (1 products)
- https://orogo.com/products/gna/nucleosides — GNA / Nucleosides (2 products)
- https://orogo.com/products/gna/phosphoramidites — GNA / Phosphoramidites (2 products)
- https://orogo.com/products/lna/nucleosides — LNA / Nucleoside Intermediates (11 products)
- https://orogo.com/products/lna/phosphoramidites — LNA / Phosphoramidites (4 products)
- https://orogo.com/products/rna-tbdms/nucleosides — Natural RNA / Nucleoside Intermediates (8 products)
- https://orogo.com/products/morpholino-pmo/nucleosides — Morpholino PMO / Nucleoside Intermediates (5 products)
- https://orogo.com/products/morpholino-pmo/subunits — Morpholino PMO / Activated Subunits (5 products)
- https://orogo.com/products/vinylphosphonate/nucleosides — 5′-(E)-VP / Nucleosides (1 products)
- https://orogo.com/products/galnac-ligand/nucleosides — GalNAc Ligands / Nucleoside Intermediates (2 products)
- https://orogo.com/products/galnac-ligand/precursors — GalNAc Ligands / Precursors (3 products)
- https://orogo.com/products/galnac-ligand/succinates — GalNAc Ligands / Succinates (2 products)
- https://orogo.com/products/galnac-ligand/supports — GalNAc Ligands / Solid Supports (1 products)
- https://orogo.com/products/conjugation-linkers/linkers — Conjugation Linkers / Linkers (2 products)
- https://orogo.com/products/terminal-modifiers/phosphoramidites — Terminal Modifiers / Phosphoramidites (6 products)
- https://orogo.com/products/lipid-ligands/phosphoramidites — Lipids and Other Ligands / Phosphoramidites (6 products)
- https://orogo.com/products/lipid-ligands/supports — Lipids and Other Ligands / Solid Supports (1 products)
- https://orogo.com/products/solid-supports/supports — Solid Supports and Precursors / Solid Supports (2 products)
- https://orogo.com/products/phosphitylation-reagents/reagents — Phosphitylation Reagents / Process Reagents (3 products)
- https://orogo.com/products/synthesis-reagents/reagents — Synthesis-Cycle Reagents / Sulfurizing Reagents (2 products)
- https://orogo.com/products/mrna-delivery/lipids — mRNA and Delivery / Lipids and LNP Excipients (6 products)
- https://orogo.com/products/n3-p5-thiophosphoramidate/nucleosides — N3′→P5′ Thiophosphoramidate / Nucleoside Intermediates (5 products)
- https://orogo.com/products/l-rna/phosphoramidites — L-RNA (Mirror-image RNA) / Phosphoramidites (4 products)
- https://orogo.com/products/2-o-nma/phosphoramidites — 2′-O-NMA / Phosphoramidites (4 products)
- https://orogo.com/products/n3-p5-thiophosphoramidate/phosphoramidites — N3′→P5′ Thiophosphoramidate / Phosphoramidites (5 products)
- https://orogo.com/products/mrna-delivery/nucleosides — mRNA and Delivery / Nucleoside Intermediates (1 products)
- https://orogo.com/products/2-o-nma/nucleosides — 2′-O-NMA / Nucleoside Intermediates (1 products)
- https://orogo.com/products/mrna-delivery/modified-ntps — mRNA and Delivery / Modified NTPs (2 products)
- https://orogo.com/products/n3-p5-thiophosphoramidate/supports — N3′→P5′ Thiophosphoramidate / Solid Supports (1 products)
- https://orogo.com/products/n3-p5-thiophosphoramidate/precursors — N3′→P5′ Thiophosphoramidate / Precursors (1 products)

## Citation and verification
Technical articles identify their publication date, authoring organization and visible public literature references. Product literature links provide scientific context and are not lot-specific evidence. Product pages are research-use catalog records for identity and planning; current specifications, availability, CoA data and supply terms must be confirmed in an OROGO quotation or lot-specific document.

For current specifications, CoA availability, lead times and custom requests, contact info@orogo.com.