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Morpholino PMO / Activated Subunits

N4-Bz protected C PMO Monomer

Quick view. An N4-benzoyl cytosine PMO monomer bearing N-trityl morpholine protection and a dimethylphosphoramidochloridate group. CAS 956139-21-2. Catalog target purity: Specification by inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.

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Chemical structure of N4-benzoyl protected cytosine PMO monomer
Chemical structure
Catalog numberOR-PM-0001
CAS number956139-21-2
PuritySpecification by inquiry
Pack sizeCustom packaging by inquiry

Catalog status

Scope. "Available for inquiry" is not a stock claim. Operating tier is a catalog-merchandising priority. Development phase and program context are shown only where the reviewed catalog source provides a mapping; they describe the chemistry platform and do not claim that OROGO supplies the named program. Annual demand is a planning-model estimate from the reviewed demand dataset, not OROGO sales, inventory, a guaranteed market size or a supply commitment.

Supply statusAvailable for inquiry
Operating tierCore
Reviewed supporting program count4
Representative chemistry-platform programcasimersen
Planning-model annual demand236.7 kg/year
Demand estimate basisPlanning model: current marketed plus clinical-stage programs
Highest development phaseMarketed
CAS statusPublished registry number

Product profile

Material identity

N4-Bz protected C PMO Monomer is classified as protected cytosine morpholino phosphoramidochloridate (Formula C37H37ClN5O5P; molecular weight 698.15).

Typical application

N4-Bz protected C PMO Monomer — Protected cytosine morpholino building block for research-use PMO synthesis.

Handling focus

For N4-Bz protected C PMO Monomer, confirm the current specification, storage conditions and downstream-method compatibility before routine use.

Names and search terms

Confirmed or normalized name variants

Useful catalog search terms

Physicochemical data

Base protectionN4-benzoyl
Morpholine nitrogen protectionTrityl
Phosphorus groupDimethylphosphoramidochloridate
SMILESCN(C)P(=O)(OC[C@@H]1CN(C[C@@H](O1)N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)C(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)Cl
InChIInChI=1S/C37H37ClN5O5P/c1-41(2)49(38,46)47-27-32-25-42(26-34(48-32)43-24-23-33(40-36(43)45)39-35(44)28-15-7-3-8-16-28)37(29-17-9-4-10-18-29,30-19-11-5-12-20-30)31-21-13-6-14-22-31/h3-24,32,34H,25-27H2,1-2H3,(H,39,40,44,45)/t32-,34+,49?/m0/s1
InChIKeyRCQVHNTXMQCQLT-AUIRFOQBSA-N
PubChem CID16662132

Release documentation

Lot-specific CoA

The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.

Analytical package

Additional HPLC, MS or NMR documentation can be agreed during technical review where available.

Related products

Feature and workflow background

These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.

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Technology platforms

Catalog-derived platform membership for navigating related chemistry and verifiable product sets.