Morpholino PMO / Nucleoside Intermediates
N6-Benzoyl-7'-OH-N-trityl morpholino adenosine
Quick view. An N6-benzoyl- and N-trityl-protected morpholino adenosine intermediate with a free 7'-hydroxymethyl group. CAS 956139-16-5. Catalog target purity: Specification by inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Catalog status
Scope. "Available for inquiry" is not a stock claim. Operating tier is a catalog-merchandising priority. Development phase and program context are shown only where the reviewed catalog source provides a mapping; they describe the chemistry platform and do not claim that OROGO supplies the named program. Annual demand is a planning-model estimate from the reviewed demand dataset, not OROGO sales, inventory, a guaranteed market size or a supply commitment.
| Supply status | Available for inquiry |
|---|---|
| Operating tier | Core |
| Reviewed supporting program count | 4 |
| Representative chemistry-platform program | casimersen |
| Planning-model annual demand | 180.2 kg/year |
| Demand estimate basis | Planning model: current marketed plus clinical-stage programs |
| Highest development phase | Marketed |
| CAS status | Published registry number |
Product profile
N6-Benzoyl-7'-OH-N-trityl morpholino adenosine is classified as morpholino pmo / nucleoside intermediates (Formula C36H32N6O3; molecular weight 596.68 g/mol).
N6-Benzoyl-7'-OH-N-trityl morpholino adenosine — Protected morpholino adenosine intermediate for PMO monomer route development and downstream functionalization.
For N6-Benzoyl-7'-OH-N-trityl morpholino adenosine, storage: Powder at -20 C; in solution at -80 C; confirm against the applicable COA.
Names and search terms
Confirmed or normalized name variants
- N6-Benzoyl-7'-hydroxy-N-trityl morpholino adenine
- PMO-A precursor
- N-[9-[(2R,6S)-6-(hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-9H-purin-6-yl]benzamide
Useful catalog search terms
- 956139-16-5
- C36H32N6O3
Physicochemical data
| SMILES | C1[C@H](O[C@H](CN1C(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)N5C=NC6=C(N=CN=C65)NC(=O)C7=CC=CC=C7)CO |
|---|---|
| Scaffold | Morpholino adenosine |
| Base protection | N6-Benzoyl |
| Morpholine protection | N-Trityl |
| Functional group | Free 7'-hydroxymethyl |
| PubChem CID | 16662127 |
| InChIKey | XFQQPEYYQOKYTE-IOWSJCHKSA-N |
| InChI | InChI=1S/C36H32N6O3/c43-23-30-21-41(36(27-15-7-2-8-16-27,28-17-9-3-10-18-28)29-19-11-4-12-20-29)22-31(45-30)42-25-39-32-33(37-24-38-34(32)42)40-35(44)26-13-5-1-6-14-26/h1-20,24-25,30-31,43H,21-23H2,(H,37,38,40,44)/t30-,31+/m0/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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