GalNAc Ligands / Precursors
Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine
Quick view. Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine is a tert-butyl-protected, three-arm scaffold identified by CAS 175724-30-8 and reported in GalNAc Ligands / Precursors conjugation routes. Catalog target purity: Specification by inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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![Chemical structure of Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine](/structures/faaa8660f1efa97d.svg)
Catalog status
Scope. "Available for inquiry" is not a stock claim. Operating tier is a catalog-merchandising priority. Development phase and program context are shown only where the reviewed catalog source provides a mapping; they describe the chemistry platform and do not claim that OROGO supplies the named program.
| Supply status | Available for inquiry |
|---|---|
| Operating tier | Priority |
| Development context | ↑ Upstream — reviewed as a supporting input; no direct development phase is assigned |
| CAS status | Published registry number |
Product profile
Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine is classified as galnac ligands / precursors (Formula C25H47NO9; molecular weight 505.64).
Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine — Reported in US12247047B2 as a tert-butyl-protected trivalent scaffold used in a GalNAc solid-support synthesis route.
For Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane
- Di-tert-butyl 3,3'-((2-amino-2-((3-(tert-butoxy)-3-oxopropoxy)methyl)propane-1,3-diyl)bis(oxy))dipropanoate
- GalNAc-L96-tert-butyl ester
Useful catalog search terms
- CAS 175724-30-8
- C25H47NO9
- KPXODPHVWBQJEG-UHFFFAOYSA-N
- GalNAc scaffold
- GalNAc
Physicochemical data
| PubChem CID | 11249159 |
|---|---|
| SMILES | CC(C)(C)OC(=O)CCOCC(COCCC(=O)OC(C)(C)C)(COCCC(=O)OC(C)(C)C)N |
| InChI | InChI=1S/C25H47NO9/c1-22(2,3)33-19(27)10-13-30-16-25(26,17-31-14-11-20(28)34-23(4,5)6)18-32-15-12-21(29)35-24(7,8)9/h10-18,26H2,1-9H3 |
| InChIKey | KPXODPHVWBQJEG-UHFFFAOYSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Reported as a protected multivalent scaffold followed by deprotection and GalNAc-arm coupling in triGalNAc material preparation.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- A defined GalNAc intermediate helps decouple ligand-linker optimization from sequence optimization.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- In-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
These points describe Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
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Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.