DNA / Phosphoramidites
DMTr-dA(Bz)-3'-CE-Phosphoramidite
Quick view. DMTr-dA(Bz)-3'-CE-Phosphoramidite is an N6-benzoyl-protected deoxyadenosine building block for research-use DNA oligonucleotide synthesis. CAS 98796-53-3. Catalog target purity: Specification by inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Catalog status
Scope. "Available for inquiry" is not a stock claim. Operating tier is a catalog-merchandising priority. Development phase and program context are shown only where the reviewed catalog source provides a mapping; they describe the chemistry platform and do not claim that OROGO supplies the named program. Annual demand is a planning-model estimate from the reviewed demand dataset, not OROGO sales, inventory, a guaranteed market size or a supply commitment.
| Supply status | Available for inquiry |
|---|---|
| Operating tier | Core |
| Reviewed supporting program count | 6 |
| Representative chemistry-platform program | eplontersen |
| Planning-model annual demand | 59.6 kg/year |
| Demand estimate basis | Planning model: current marketed plus clinical-stage programs |
| Highest development phase | Marketed |
| CAS status | Published registry number |
Product profile
DMTr-dA(Bz)-3'-CE-Phosphoramidite is classified as protected deoxyadenosine phosphoramidite (Formula C47H52N7O7P; molecular weight 857.90).
DMTr-dA(Bz)-3'-CE-Phosphoramidite — N6-benzoyl-protected deoxyadenosine phosphoramidite building block for research-use DNA oligonucleotide synthesis.
For DMTr-dA(Bz)-3'-CE-Phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- DMT-dA(Bz) Phosphoramidite
- Bz-dA Beta-Cyanoethyl Phosphoramidite
- 5'-O-DMT-N6-benzoyl-2'-deoxyadenosine-3'-CE Phosphoramidite
Useful catalog search terms
- 98796-53-3
- C47H52N7O7P
- PubChem 9962711
- USP 1152032
- DNA Phosphoramidites
Physicochemical data
| Base protection | N6-benzoyl |
|---|---|
| Synthesis format | 5'-DMTr and 3'-2-cyanoethyl N,N-diisopropyl phosphoramidite |
| Physical form | White to pale yellow powder |
| Water content reference | ≤0.3% |
| InChIKey | GGDNKEQZFSTIMJ-AKWFTNRHSA-N |
| InChI | InChI=1S/C47H52N7O7P/c1-32(2)54(33(3)4)62(59-27-13-26-48)61-40-28-42(53-31-51-43-44(49-30-50-45(43)53)52-46(55)34-14-9-7-10-15-34)60-41(40)29-58-47(35-16-11-8-12-17-35,36-18-22-38(56-5)23-19-36)37-20-24-39(57-6)25-21-37/h7-12,14-25,30-33,40-42H,13,27-29H2,1-6H3,(H,49,50,52,55)/t40-,41+,42+,62?/m0/s1 |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)O[C@H]1C[C@@H](O[C@@H]1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=NC6=C(N=CN=C65)NC(=O)C7=CC=CC=C7 |
| PubChem CID | 9962711 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the DNA Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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