DNA / Phosphoramidites
DMTr-5-Me-dC(Bz)-3'-CE-Phosphoramidite
Quick view. DMTr-5-Me-dC(Bz)-3'-CE-Phosphoramidite is an N4-benzoyl-protected 5-methyl-deoxycytidine building block for research-use oligonucleotide synthesis. CAS 105931-57-5. Catalog target purity: ≥98.0% (HPLC). Availability: Inquiry only — contact OROGO to confirm current availability.
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Catalog status
Scope. "Available for inquiry" is not a stock claim. Operating tier is a catalog-merchandising priority. Development phase and program context are shown only where the reviewed catalog source provides a mapping; they describe the chemistry platform and do not claim that OROGO supplies the named program. Annual demand is a planning-model estimate from the reviewed demand dataset, not OROGO sales, inventory, a guaranteed market size or a supply commitment.
| Supply status | Available for inquiry |
|---|---|
| Operating tier | Core |
| Reviewed supporting program count | 7 |
| Representative chemistry-platform program | donidalorsen |
| Planning-model annual demand | 20.3 kg/year |
| Demand estimate basis | Planning model: current marketed plus clinical-stage programs |
| Highest development phase | Marketed |
| CAS status | Published registry number |
Product profile
DMTr-5-Me-dC(Bz)-3'-CE-Phosphoramidite is classified as protected 5-methyl-deoxycytidine phosphoramidite (Formula C47H54N5O8P; molecular weight 847.90).
DMTr-5-Me-dC(Bz)-3'-CE-Phosphoramidite — N4-benzoyl-protected 5-methyl-deoxycytidine phosphoramidite building block for research-use oligonucleotide synthesis.
For DMTr-5-Me-dC(Bz)-3'-CE-Phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 5-Me Bz dC Beta-Cyanoethyl Phosphoramidite
- DMT-5-Me-dC(Bz) Phosphoramidite
- N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
Useful catalog search terms
- 105931-57-5
- C47H54N5O8P
- PubChem 15374208
- USP 1152033
- ONT105931575
- PA029
- DNA Phosphoramidites
Physicochemical data
| Base protection | N4-benzoyl |
|---|---|
| Synthesis format | 5'-DMTr and 3'-2-cyanoethyl N,N-diisopropyl phosphoramidite |
| InChIKey | AGMUHEZFYUECLW-QUZMAVINSA-N |
| InChI | InChI=1S/C47H54N5O8P/c1-32(2)52(33(3)4)61(58-28-14-27-48)60-41-29-43(51-30-34(5)44(50-46(51)54)49-45(53)35-15-10-8-11-16-35)59-42(41)31-57-47(36-17-12-9-13-18-36,37-19-23-39(55-6)24-20-37)38-21-25-40(56-7)26-22-38/h8-13,15-26,30,32-33,41-43H,14,28-29,31H2,1-7H3,(H,49,50,53,54)/t41-,42+,43+,61?/m0/s1 |
| SMILES | CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)[C@H]3C[C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N |
| PubChem CID | 15374208 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the DNA Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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