2′-MOE / Phosphoramidites
DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-(L)-PSM-Phosphoramidite
Quick view. A protected 2'-O-MOE 5-methylcytidine building block bearing an L-PSM phosphoramidite group for oligonucleotide synthesis research. CAS 2379296-21-4. Catalog target purity: Specification by inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Catalog status
Scope. "Available for inquiry" is not a stock claim. Operating tier is a catalog-merchandising priority. Development phase and program context are shown only where the reviewed catalog source provides a mapping; they describe the chemistry platform and do not claim that OROGO supplies the named program.
| Supply status | Available for inquiry |
|---|---|
| Operating tier | Priority |
| Development context | ↑ Upstream — reviewed as a supporting input; no direct development phase is assigned |
| CAS status | Published registry number |
Product profile
DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-(L)-PSM-Phosphoramidite is classified as 2′-moe / phosphoramidites (Formula C53H57N4O12PS; molecular weight 1005.10).
DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-(L)-PSM-Phosphoramidite — L-PSM 2'-O-MOE 5-methylcytidine building block for oligonucleotide synthesis research.
For DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-(L)-PSM-Phosphoramidite, mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Names and search terms
Confirmed or normalized name variants
- DMT-2'-O-MOE-5-Me-rC(Bz)-3'-(L)-PSM-Phosphoramidite
Useful catalog search terms
- CAS 2379296-21-4
- PubChem 178421349
- C53H57N4O12PS
Physicochemical data
| PubChem CID | 178421349 |
|---|---|
| InChIKey | UUMRAIRUULBYGT-PRACXZEXSA-N |
| Phosphoramidite configuration | L-PSM |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-(L)-PSM-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the 2'-O-MOE Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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