2′-OMe / Phosphoramidites
DMTr-2'-O-Me-rU-3'-(L)-DPSE-Phosphoramidite
Quick view. DMTr-2'-O-Me-rU-3'-(L)-DPSE-Phosphoramidite is a 2'-O-methyl uridine building block bearing an L-DPSE phosphoramidite auxiliary for research-use oligonucleotide synthesis. CAS 1528733-97-2. Catalog target purity: Specification by inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Catalog status
Scope. "Available for inquiry" is not a stock claim. Operating tier is a catalog-merchandising priority. Development phase and program context are shown only where the reviewed catalog source provides a mapping; they describe the chemistry platform and do not claim that OROGO supplies the named program.
| Supply status | Available for inquiry |
|---|---|
| Operating tier | Priority |
| Reviewed supporting program count | 4 |
| Representative chemistry-platform program | WVE-N531 |
| Highest development phase | Phase III |
| CAS status | Published registry number |
Related product programs
Product profile
DMTr-2'-O-Me-rU-3'-(L)-DPSE-Phosphoramidite is classified as protected 2'-o-methyl ribouridine phosphoramidite (Formula C50H54N3O9PSi; molecular weight 900.00).
DMTr-2'-O-Me-rU-3'-(L)-DPSE-Phosphoramidite — 2'-O-methyl uridine building block bearing an L-DPSE phosphoramidite auxiliary for research-use oligonucleotide synthesis.
For DMTr-2'-O-Me-rU-3'-(L)-DPSE-Phosphoramidite, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- DMT-2'-O-Me-rU-3'-(L)-DPSE-Phosphoramidite
Useful catalog search terms
- 1528733-97-2
- PubChem 178421350
- C50H54N3O9PSi
- Synthgene PA240
- 2'-O-Me Phosphoramidites
Physicochemical data
| Ribose modification | 2'-O-methyl |
|---|---|
| 5' protection | DMTr |
| Phosphorus auxiliary | L-DPSE |
| InChIKey | ZCWZYMJOKSJYRG-ISAGSOKLSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe DMTr-2'-O-Me-rU-3'-(L)-DPSE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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2'-O-Me Phosphoramidites · CAS: 1528733-91-6
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OR-2OMP-00325'-O-DMTr-2'-O-Me-N6-benzoyladenosine-3'-(L)-PSM phosphoramidite
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OR-2OMP-0033DMTr-2'-O-Me-rC(Ac)-3'-(L)-PSM-Phosphoramidite
2'-O-Me Phosphoramidites · CAS: N/A
OR-2OMP-00365'-O-DMTr-2'-O-Me-N2-isobutyrylguanosine-3'-(D)-DPSE phosphoramidite
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OR-2OMP-00375'-O-DMTr-2'-O-Me-N2-isobutyrylguanosine-3'-(L)-DPSE phosphoramidite
2'-O-Me Phosphoramidites · CAS: 2227139-95-7
Product-family literature
These publications provide peer-reviewed context for the 2'-O-Me Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.