Synthesis-Cycle Reagents / Coupling Activators
5-(Benzylthio)-1H-tetrazole (BTT)
Quick view. 5-(Benzylthio)-1H-tetrazole (BTT) is a defined tetrazole reagent used as a coupling activator in research-use phosphoramidite-based oligonucleotide synthesis. CAS 21871-47-6. Catalog target purity: Specification by inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Catalog status
Scope. "Available for inquiry" is not a stock claim. Operating tier is a catalog-merchandising priority. Development phase and program context are shown only where the reviewed catalog source provides a mapping; they describe the chemistry platform and do not claim that OROGO supplies the named program. Annual demand is a planning-model estimate from the reviewed demand dataset, not OROGO sales, inventory, a guaranteed market size or a supply commitment.
| Supply status | Available for inquiry |
|---|---|
| Operating tier | Core |
| Reviewed supporting program count | 17 |
| Representative chemistry-platform program | donidalorsen |
| Planning-model annual demand | 1692.5 kg/year |
| Demand estimate basis | Planning model: current marketed plus clinical-stage programs |
| Highest development phase | Marketed |
| CAS status | Published registry number |
Product profile
5-(Benzylthio)-1H-tetrazole (BTT) is classified as synthesis-cycle reagents / coupling activators (Formula C8H8N4S; molecular weight 192.24).
5-(Benzylthio)-1H-tetrazole (BTT) — Coupling activator for phosphoramidite-based research-use oligonucleotide synthesis.
For 5-(Benzylthio)-1H-tetrazole (BTT), confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- BTT
- BMT
- 5-Benzylmercapto-1H-tetrazole
- 5-[(Phenylmethyl)thio]-1H-tetrazole
Useful catalog search terms
- 5-Benzylthio-1H-tetrazole (BTT)
- CAS 21871-47-6
- 5-benzylsulfanyl-2H-tetrazole
- phosphoramidite coupling activator
Physicochemical data
| Systematic name | 5-benzylsulfanyl-2H-tetrazole |
|---|---|
| InChIKey | GXGKKIPUFAHZIZ-UHFFFAOYSA-N |
| InChI | InChI=1S/C8H8N4S/c1-2-4-7(5-3-1)6-13-8-9-11-12-10-8/h1-5H,6H2,(H,9,10,11,12) |
| SMILES | C1=CC=C(C=C1)CSC2=NNN=N2 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
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