Synthesis-Cycle Reagents / Coupling Activators
4,5-Dicyanoimidazole (DCI)
Quick view. 4,5-Dicyanoimidazole (DCI) is a defined heterocyclic coupling activator used with nucleoside phosphoramidites in research-use solid-phase oligonucleotide synthesis. CAS 1122-28-7. Catalog target purity: Specification by inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Catalog status
Scope. "Available for inquiry" is not a stock claim. Operating tier is a catalog-merchandising priority. Development phase and program context are shown only where the reviewed catalog source provides a mapping; they describe the chemistry platform and do not claim that OROGO supplies the named program. Annual demand is a planning-model estimate from the reviewed demand dataset, not OROGO sales, inventory, a guaranteed market size or a supply commitment.
| Supply status | Available for inquiry |
|---|---|
| Operating tier | Core |
| Reviewed supporting program count | 17 |
| Representative chemistry-platform program | donidalorsen |
| Planning-model annual demand | 1692.5 kg/year |
| Demand estimate basis | Planning model: current marketed plus clinical-stage programs |
| Highest development phase | Marketed |
| CAS status | Published registry number |
Product profile
4,5-Dicyanoimidazole (DCI) is classified as synthesis-cycle reagents / coupling activators (Formula C5H2N4; molecular weight 118.10).
4,5-Dicyanoimidazole (DCI) — Coupling activator for nucleoside phosphoramidites in research-use solid-phase oligonucleotide synthesis.
For 4,5-Dicyanoimidazole (DCI), confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- DCI
- 4,5-Imidazoledicarbonitrile
- 1H-imidazole-4,5-dicarbonitrile
Useful catalog search terms
- CAS 1122-28-7
- phosphoramidite coupling activator
Physicochemical data
| Systematic name | 1H-imidazole-4,5-dicarbonitrile |
|---|---|
| InChI | InChI=1S/C5H2N4/c6-1-4-5(2-7)9-3-8-4/h3H,(H,8,9) |
| InChIKey | XGDRLCRGKUCBQL-UHFFFAOYSA-N |
| SMILES | C1=NC(=C(N1)C#N)C#N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
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Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.