Natural RNA / Nucleoside Intermediates
2'-O-TBDMS-uridine
Quick view. A uridine nucleoside protected as a tert-butyldimethylsilyl ether at the ribose 2'-oxygen. CAS 54925-71-2. Catalog target purity: Specification by inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Catalog status
Scope. "Available for inquiry" is not a stock claim. Operating tier is a catalog-merchandising priority. Development phase and program context are shown only where the reviewed catalog source provides a mapping; they describe the chemistry platform and do not claim that OROGO supplies the named program.
| Supply status | Available for inquiry |
|---|---|
| Operating tier | Priority |
| Development context | ↑ Upstream — reviewed as a supporting input; no direct development phase is assigned |
| CAS status | Published registry number |
Product profile
2'-O-TBDMS-uridine is classified as 2'-o-silyl-protected uridine (Formula C15H26N2O6Si; molecular weight 358.46 g/mol).
2'-O-TBDMS-uridine is associated with uridine-containing substrates for U-position incorporation in RNA or modified RNA studies.
For 2'-O-TBDMS-uridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2'-TBDMS-rU
Useful catalog search terms
- 54925-71-2
- 11233661
- AYQZFVZTNUOLCQ-OJAKKHQRSA-N
Physicochemical data
| PubChem CID | 11233661 |
|---|---|
| IUPAC name | 1-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
| InChIKey | AYQZFVZTNUOLCQ-OJAKKHQRSA-N |
| InChI | InChI=1S/C15H26N2O6Si/c1-15(2,3)24(4,5)23-12-11(20)9(8-18)22-13(12)17-7-6-10(19)16-14(17)21/h6-7,9,11-13,18,20H,8H2,1-5H3,(H,16,19,21)/t9-,11-,12-,13-/m1/s1 |
| SMILES | CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)CO)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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