mRNA and Delivery / mRNA Cap Analogs
beta-S-ARCA (D1) ammonium salt
Quick view. The D1 diastereomer of a beta-phosphorothioate anti-reverse cap analogue in a generic ammonium presentation for in-vitro RNA and capping research. CAS and composition refer to the inner salt. CAS 1093268-63-3. Catalog target purity: Specification by inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Catalog status
Scope. "Available for inquiry" is not a stock claim. Operating tier is a catalog-merchandising priority. Development phase and program context are shown only where the reviewed catalog source provides a mapping; they describe the chemistry platform and do not claim that OROGO supplies the named program.
| Supply status | Available for inquiry |
|---|---|
| Operating tier | Priority |
| Reviewed supporting program count | 4 |
| Representative chemistry-platform program | autogene cevumeran |
| Highest development phase | Phase II |
| CAS status | Published registry number |
Product profile
beta-S-ARCA (D1) ammonium salt is classified as mrna and delivery / mrna cap analogs.
beta-S-ARCA (D1) ammonium salt — Phosphorothioate anti-reverse cap analogue material for in-vitro RNA and capping research.
For beta-S-ARCA (D1) ammonium salt, capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
Names and search terms
Confirmed or normalized name variants
- beta-S-ARCA D1
- m2(7,2'-O)GppSpG D1
- CAP3811
- N9Y6S0ZG5C
Useful catalog search terms
- CAS 1093268-63-3
Physicochemical data
| Related CAS | 1093268-63-3 (D1 inner salt) |
|---|---|
| Inner-salt molecular formula | C22H31N10O17P3S |
| Inner-salt molecular weight | 832.52 |
| Diastereomer | D1 |
| Counterion presentation | Ammonium; stoichiometry not specified |
| Structural shorthand | m2(7,2'-O)GppSpG D1 |
| Covalent InChIKey | DOOBEITVZIIXPE-XJGHKLLTSA-N |
| Covalent InChI | InChI=1S/C22H31N10O17P3S/c1-30-6-32(16-10(30)18(37)29-22(24)27-16)20-14(43-2)12(34)8(47-20)4-45-51(40,41)49-52(42,53)48-50(38,39)44-3-7-11(33)13(35)19(46-7)31-5-25-9-15(31)26-21(23)28-17(9)36/h5-8,11-14,19-20,33-35H,3-4H2,1-2H3,(H8-,23,24,26,27,28,29,36,37,38,39,40,41,42,53)/t7-,8-,11-,12-,13-,14-,19-,20-,52?/m1/s1 |
| Covalent SMILES | CO[C@@H]1[C@H](O)[C@@H](COP(=O)([O-])OP(=O)(S)OP(=O)(O)OC[C@H]2O[C@@H](n3cnc4c(=O)nc(N)[nH]c43)[C@H](O)[C@@H]2O)O[C@H]1n1c[n+](C)c2c(=O)nc(N)[nH]c21 |
| Canonical covalent SMILES | CO[C@@H]1[C@H](O)[C@@H](COP(=O)([O-])OP(=O)(S)OP(=O)(O)OC[C@H]2O[C@@H](n3cnc4c(=O)nc(N)[nH]c43)[C@H](O)[C@@H]2O)O[C@H]1n1c[n+](C)c2c(=O)nc(N)[nH]c21 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Cap analog selection can influence capping efficiency, orientation and downstream translation-related performance.
Method limitations
- Capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
These points describe beta-S-ARCA (D1) ammonium salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
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Technology platforms
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