GNA / Phosphoramidites
DMTr-A(Bz)-(S)-GNA Phosphoramidite
Quick view. DMTr-A(Bz)-(S)-GNA Phosphoramidite is a protected adenine (S)-GNA phosphoramidite identified by CAS 851050-24-3. Catalog target purity: Specification by inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Catalog status
Scope. "Available for inquiry" is not a stock claim. Operating tier is a catalog-merchandising priority. Development phase and program context are shown only where the reviewed catalog source provides a mapping; they describe the chemistry platform and do not claim that OROGO supplies the named program.
| Supply status | Available for inquiry |
|---|---|
| Operating tier | Priority |
| Reviewed supporting program count | 4 |
| Representative chemistry-platform program | zilebesiran |
| Highest development phase | Phase III |
| CAS status | Published registry number |
Product profile
DMTr-A(Bz)-(S)-GNA Phosphoramidite is classified as gna / phosphoramidites (Formula C45H50N7O6P; molecular weight 815.90).
DMTr-A(Bz)-(S)-GNA Phosphoramidite is associated with adenine-containing building blocks or substrates for A-position incorporation and analytical comparison.
For DMTr-A(Bz)-(S)-GNA Phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- (S)-GNA-A(Bz)-phosphoramidite
- N6-Bz-A-(S)-GNA phosphoramidite
- DMT-A(Bz)-(S)-GNA Phosphoramidite
- GNA-(S)-A(Bz)-Phosphoramidite
Useful catalog search terms
- CAS 851050-24-3
- OR-GP-0006
- GNA Phosphoramidites
Physicochemical data
| InChIKey | RHPZFMWWZNRHHT-MXHUVDEASA-N |
|---|---|
| InChI | InChI=1S/C45H50N7O6P/c1-32(2)52(33(3)4)59(57-27-13-26-46)58-40(28-51-31-49-41-42(47-30-48-43(41)51)50-44(53)34-14-9-7-10-15-34)29-56-45(35-16-11-8-12-17-35,36-18-22-38(54-5)23-19-36)37-20-24-39(55-6)25-21-37/h7-12,14-25,30-33,40H,13,27-29H2,1-6H3,(H,47,48,50,53)/t40-,59?/m0/s1 |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)O[C@@H](CN1C=NC2=C(N=CN=C21)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC |
| Canonical SMILES | CC(C)N(C(C)C)P(OCCC#N)O[C@@H](CN1C=NC2=C(N=CN=C21)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC |
| PubChem CID | 102511305 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
Product-family literature
These publications provide peer-reviewed context for the GNA Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.