Synthesis-Cycle Reagents / Sulfurizing Reagents
DDTT Sulfurizing Reagent
Quick view. A dithiazole sulfur-transfer reagent used in the sulfurization step that converts phosphite-triester linkages to phosphorothioate linkages during oligonucleotide synthesis. CAS 1192027-04-5. Catalog target purity: Specification by inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Catalog status
Scope. "Available for inquiry" is not a stock claim. Operating tier is a catalog-merchandising priority. Development phase and program context are shown only where the reviewed catalog source provides a mapping; they describe the chemistry platform and do not claim that OROGO supplies the named program. Annual demand is a planning-model estimate from the reviewed demand dataset, not OROGO sales, inventory, a guaranteed market size or a supply commitment.
| Supply status | Available for inquiry |
|---|---|
| Operating tier | Core |
| Reviewed supporting program count | 17 |
| Representative chemistry-platform program | donidalorsen |
| Planning-model annual demand | 476.6 kg/year |
| Demand estimate basis | Planning model: current marketed plus clinical-stage programs |
| Highest development phase | Marketed |
| CAS status | Published registry number |
Product profile
DDTT Sulfurizing Reagent is classified as synthesis-cycle reagents / sulfurizing reagents (Formula C5H7N3S3; molecular weight 205.32).
DDTT Sulfurizing Reagent — Sulfurization step in phosphorothioate oligonucleotide synthesis workflows.
For DDTT Sulfurizing Reagent, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- DDTT
- N,N-Dimethyl-N'-(3-thioxo-3H-1,2,4-dithiazol-5-yl)formimidamide
- [(Dimethylamino-methylidene)amino]-3H-1,2,4-dithiazoline-3-thione
Useful catalog search terms
- CAS 1192027-04-5
- Oligonucleotide sulfur-transfer reagent
Physicochemical data
| InChIKey | YRDSDHFBUHFDPG-UHFFFAOYSA-N |
|---|---|
| Systematic name | N,N-Dimethyl-N'-(3-thioxo-3H-1,2,4-dithiazol-5-yl)formimidamide |
| Reagent class | Dithiazole sulfur-transfer reagent |
| SMILES | CN(C)C=NC1=NC(=S)SS1 |
| InChI | InChI=1S/C5H7N3S3/c1-8(2)3-6-4-7-5(9)11-10-4/h3H,1-2H3 |
| PubChem CID | 75046917 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
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Technology platforms
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